Tofacent 10 is an effective treatment for moderate to severe rheumatoid arthritis, reducing pain and inflammation and slowing joint damage progression. Regular monitoring and adherence to prescribed doses are crucial for managing the condition and minimizing side effects.
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Tofacitinib belongs to the group of medicines called Antirheumatics. It is used to manage inflammatory diseases such as rheumatoid arthritis (chronic inflammatory diseases affecting the joints, causing pain and swelling), psoriatic arthritis (an arthritic condition that occurs in an individual with psoriasis), ulcerative colitis (ulcerative inflammation of the digestive tract) and ankylosing spondylitis (fusion of bones in the spine).
Tofacitinib is not recommended for patients with severe liver diseases, bloodstream infections, or active tuberculosis and should be used cautiously in those with conditions increasing infection risk, chronic diseases, cancer risk, smoking habits, lactose intolerance, gastrointestinal issues, high blood pressure, high cholesterol, risk of blood clots, vaccination plans, or recent major surgery.
Consuming alcohol with Tofacent 10 causes harmful side effects.
Tofacent 10mg Tablet is not recommended for use in pregnant women or women planning to have a baby. If you are a woman of childbearing age, you should use effective birth control during management and for at least 4 weeks after the last dose. Consult your doctor before taking it.
Tofacent 10mg Tablet is not recommended for use in breastfeeding women. Consult your doctor before taking it.
Tofacent 10mg Tablet does not affect your ability to drive or use machines.
Tofacent 10mg Tablet should be taken with caution in patients with kidney disease. The dose will be adjusted by your doctor Consult your doctor before taking it.
Tofacent 10mg Tablet is not recommended in patients with severe liver problems such as cirrhosis (scarring of the liver). It should be used with caution in patients having other liver diseases such as hepatitis B or hepatitis C. Dose will be adjusted by your doctor. Consult your doctor before taking it.
Tofacitinib is a Janus kinase (JAK) inhibitor. By blocking JAKs, it prevents the phosphorylation and activation of STATs, key players in the inflammatory response, thereby reducing inflammation and joint damage.
Common adverse reactions (≥2% of patients):
Tofacitinib is a partial and reversible Janus kinase (JAK) inhibitor. It interferes with the body's response to cytokine signals by preventing the activation of the JAK-STAT pathway, thereby reducing inflammation and immune responses. This mechanism helps decrease tissue inflammation and joint damage in rheumatoid arthritis.
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